E. Howard

Latest

• Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain
• Publisher Correction: Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain (Scientific Reports (2018) DOI: 10.1038/s41598-018-27606-8)
• Structural Basis of Outstanding Multivalent Effects in Jack Bean α-Mannosidase Inhibition
• Importance of protonation states for the binding of ligands to pharmaceutical targets
• Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
• Crystal packing modifies ligand binding affinity: The case of aldose reductase
• Incorporation of methyl-protonated valine and leucine residues into deuterated ocean pout type III antifreeze protein: expression, crystallization and preliminary neutron diffraction studies
• Neutron macromolecular crystallography with LADI-III
• Perdeuteration, purification, crystallization and preliminary neutron diffraction of an ocean pout type III antifreeze protein
• Model of the catalytic mechanism of human aldose reductase based on quantum chemical calculations
• The effect of stereochemistry upon carbohydrate hydration. A molecular dynamics simulation of β-d-galactopyranose and (α,β)-d-talopyranose
• Conformations of erythritol and L-threitol in aqueous solution in relation to sweetness properties: A molecular dynamics simulation